From GWAS to gene: what are the essential analyses and how do we bring them together using heterogeneous stock rats?

Goals of this webinar:
Heterogeneous stock (HS) rats are an outbred population that was created in 1984 by intercrossing 8 inbred strains. The Center for GWAS in Outbred Rats (http://www.ratgenes.org) has developed a suite of analysis tools for analyzing genome wide association studies (GWAS) in HS rats

  • explain the HS rat population and their history

  • describe the automated pipeline that performs GWAS in HS rats

  • explore the fine mapping of associated regions and explain the various secondary analyses that we use to prioritize genes within associated intervals

Presented by:
Dr. Abraham Palmer
Professor and Vice Chair for Basic Research
Department of Psychiatry
University of California San Diego